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결과부분만 번역좀 해주세요!!!의학용어부분은 그냥 영어로 써두시면 알아서 해석하겠습니다...뭔말인지말 알수있게 해주세요-_-;;;;
내공 100겁니다..올인이에요 올인!!!
Results
One hundred forty-six patients were originally enrolled
in the Durham County Stroke Study. They were
randomly assigned to the test set or training set at the
time of analysis. Twenty-three patients died before the
6-month assessment, 17 did not have 6-month motor
scores recorded, and two were excluded because baseline
measures could not be obtained. The remaining 104
patients, 54 in the training set and 50 in the test set,
were available for analysis. There were no differences in
mortality or missing 6-month measurements between
the two sets. Table 1 gives the demographic characteristics,
initial total Fugl-Meyer scores, and initial Fugl-
Meyer motor and sensory subscores for both groups.
None of the differences between the training set and
test set were statistically significant. As expected, patients
who died had more severe initial motor deficits
than those who survived (33.4 versus 57.5,/?=0.002).
To assess how well and how soon after stroke
6-month motor recovery could be predicted, the potential
predictors of Barthel Index scores and Fugl-Meyer
motor and sensory scores were analyzed by regression.
Regression analysis performed on the training set data
revealed that 53.2% of the variance of 6-month Fugl-
Meyer motor score could be explained by the baseline
Fugl-Meyer motor score alone (Table 2). The best
model based on data available at 5 days after stroke
included the motor and sensory scores and explained
74.2% of the variance of 6-month Fugl-Meyer score.
The best predictive model after 30 days included only
the 30-day motor score and explained 86.2% of the
variance in motor scores after 6 months. The results
obtained with the training set were confirmed when the
best models at each time point were subsequently
applied to the test set (Table 2).
The most dramatic recovery in motor function occurred
over the first 30 days, regardless of the initial
severity of the stroke (Figure 1). However, the moderate
and most severe stroke patients continued to experience
some recovery for 30-90 days (Figure 1). Nine
percent of patients classified as severe at baseline
improved to moderate levels of motor impairment by 6
months. Twenty-five percent of these initially severe
patients improved to mild levels of impairment, and 3%
achieved full motor recovery. In contrast, only 16% of
patients still classified as severe after 30 days improved
to achieve moderate deficits, and none had mild deficits
after 6 months.
Recovery of ADL as measured with the Barthel Index
paralleled the motor recovery patterns (Figure 2). The
correlations between the Fugl-Meyer score and the
Barthel Index score at 5, 30, 90, and 180 days after
stroke were computed. They ranged from r=0.80 to 0.91
(p< 0.001). Table 3 gives the percentages of patients at
each severity stratum at baseline, 5 days, and 30 days
after stroke who achieved assisted independence in
ADL (Barthel Index score of >6027) and who had
complete functional recoveries (Barthel Index score of
100) 6 months after stroke. (A Barthel Index score of
>60 was chosen in this study because Granger and
colleagues27 have reported that 60 is a pivotal score.)
Most patients with severe initial motor deficits never
achieved complete recovery in ADL (Table 3). If the
severe motor deficit persisted at 30 days, less than 10%
of the patients achieved 6-month Barthel scores of 100,
and only 56% achieved >60 points on the Barthel ADL
Index.
If therapeutic planning is to be effective, information
about both the predictability and rate of recovery after
stroke are essential. This information is also valuable in
designing clinical trials that evaluate efficacy of intervention.
The degree and rate of recovery have significant
influences on the sample sizes required to demonstrate
an effect of treatment. Table 4 gives sample sizes
required to show a 50% improvement in the residual
motor deficit after 6 months for each severity stratum at
baseline, 5 days, and 30 days after stroke.26 The number
of patients needed for a clinical intervention trial is
influenced by both the length of time after stroke and
the severity of the stroke at any time point.
다음주에 발표해야 하는데 대충 무슨 내용인지는 알겠는제 자세한 내용을 모르겠어요!ㅠ_ㅠ
결과부분만 번역좀 해주세요!!!의학용어부분은 그냥 영어로 써두시면 알아서 해석하겠습니다...뭔말인지말 알수있게 해주세요-_-;;;;
내공 100겁니다..올인이에요 올인!!!
Results
One hundred forty-six patients were originally enrolled
in the Durham County Stroke Study. They were
randomly assigned to the test set or training set at the
time of analysis. Twenty-three patients died before the
6-month assessment, 17 did not have 6-month motor
scores recorded, and two were excluded because baseline
measures could not be obtained. The remaining 104
patients, 54 in the training set and 50 in the test set,
were available for analysis. There were no differences in
mortality or missing 6-month measurements between
the two sets. Table 1 gives the demographic characteristics,
initial total Fugl-Meyer scores, and initial Fugl-
Meyer motor and sensory subscores for both groups.
None of the differences between the training set and
test set were statistically significant. As expected, patients
who died had more severe initial motor deficits
than those who survived (33.4 versus 57.5,/?=0.002).
To assess how well and how soon after stroke
6-month motor recovery could be predicted, the potential
predictors of Barthel Index scores and Fugl-Meyer
motor and sensory scores were analyzed by regression.
Regression analysis performed on the training set data
revealed that 53.2% of the variance of 6-month Fugl-
Meyer motor score could be explained by the baseline
Fugl-Meyer motor score alone (Table 2). The best
model based on data available at 5 days after stroke
included the motor and sensory scores and explained
74.2% of the variance of 6-month Fugl-Meyer score.
The best predictive model after 30 days included only
the 30-day motor score and explained 86.2% of the
variance in motor scores after 6 months. The results
obtained with the training set were confirmed when the
best models at each time point were subsequently
applied to the test set (Table 2).
The most dramatic recovery in motor function occurred
over the first 30 days, regardless of the initial
severity of the stroke (Figure 1). However, the moderate
and most severe stroke patients continued to experience
some recovery for 30-90 days (Figure 1). Nine
percent of patients classified as severe at baseline
improved to moderate levels of motor impairment by 6
months. Twenty-five percent of these initially severe
patients improved to mild levels of impairment, and 3%
achieved full motor recovery. In contrast, only 16% of
patients still classified as severe after 30 days improved
to achieve moderate deficits, and none had mild deficits
after 6 months.
Recovery of ADL as measured with the Barthel Index
paralleled the motor recovery patterns (Figure 2). The
correlations between the Fugl-Meyer score and the
Barthel Index score at 5, 30, 90, and 180 days after
stroke were computed. They ranged from r=0.80 to 0.91
(p< 0.001). Table 3 gives the percentages of patients at
each severity stratum at baseline, 5 days, and 30 days
after stroke who achieved assisted independence in
ADL (Barthel Index score of >6027) and who had
complete functional recoveries (Barthel Index score of
100) 6 months after stroke. (A Barthel Index score of
>60 was chosen in this study because Granger and
colleagues27 have reported that 60 is a pivotal score.)
Most patients with severe initial motor deficits never
achieved complete recovery in ADL (Table 3). If the
severe motor deficit persisted at 30 days, less than 10%
of the patients achieved 6-month Barthel scores of 100,
and only 56% achieved >60 points on the Barthel ADL
Index.
If therapeutic planning is to be effective, information
about both the predictability and rate of recovery after
stroke are essential. This information is also valuable in
designing clinical trials that evaluate efficacy of intervention.
The degree and rate of recovery have significant
influences on the sample sizes required to demonstrate
an effect of treatment. Table 4 gives sample sizes
required to show a 50% improvement in the residual
motor deficit after 6 months for each severity stratum at
baseline, 5 days, and 30 days after stroke.26 The number
of patients needed for a clinical intervention trial is
influenced by both the length of time after stroke and
the severity of the stroke at any time point.
